CLINICAL SCIENCE Can We Measure Corneal Biomechanical Changes After Collagen Cross-Linking in Eyes With Keratoconus?—A Pilot Study
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چکیده
Methods: Ten eyes of 10 patients aged 26.5 6 5.7 (mean 6 SD) years with progressive keratoconus were treated with UV-A– riboflavin CXL and assessed with the Ocular Response Analyzer (ORA) that measured corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal compensated intraocular pressure (IOPcc). Intraocular pressure was also measured by Goldmann applanation tonometry (GAT-IOP). Patients were assessed with ORA preoperatively, at week 1, months 1, 3, and 6 after treatment. Postoperative measurements at each visit were compared with preoperative values.
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ویژگیهای بیومکانیکی قرنیه در بیماران مبتلا به کراتوکونوس و ارتباط آن با شدت بیماری
Background and Objective: Keratoconus is a disorder in cornea characterized by constant thinning and prominence that can result in vision defect. Due to ultrasonic changes in the corneal structure caused by keratoconus disease, its rigidity and biomechanical properties are subject to some changes. In this regard, the present study was conducted to determine the correlation of biomechanical feat...
متن کاملIn vivo biomechanical changes after corneal collagen cross-linking for keratoconus and corneal ectasia: 1-year analysis of a randomized, controlled, clinical trial.
PURPOSE To investigate the in vivo, corneal, biomechanical changes after corneal collagen cross-linking (CXL) using the Ocular Response Analyzer (ORA) in patients with keratoconus and post-laser in situ keratomileusis (LASIK) ectasia. METHODS Single-center, prospective, randomized, controlled, clinical trial. After CXL (69 eyes, 46 keratoconus and 23 post-LASIK), corneal hysteresis (CH) and c...
متن کاملAccelerated versus conventional corneal collagen cross-linking in the treatment of mild keratoconus: a comparative study
AIM To evaluate the use of accelerated corneal collagen cross-linking in the management of mild and moderate progressive keratoconus in comparison with conventional cross-linking. PATIENTS AND METHODS Prospective randomized interventional case-control clinical trial. A total 25 eyes of 18 patients were randomly divided into two groups: group A included 14 eyes that received accelerated collag...
متن کاملClinical and corneal biomechanical changes after collagen cross-linking with riboflavin and UV irradiation in patients with progressive keratoconus: results after 2 years of follow-up.
PURPOSE To assess the biomechanical and keratometric effects and the safety of treatment of progressive keratoconus with UV-riboflavin collagen cross-linking (CXL). METHODS This is a prospective clinical controlled study. Fourteen eyes of 14 patients with progressive keratoconus were treated with CXL after corneal deepithelization. Patients were assessed preoperatively, at week 1 and at month...
متن کاملCorneal collagen cross-linking for keratoconus and post-LASIK ectasia.
Introduction. To determine the effect of corneal collagen cross-linking treatment on keratoconus and post-LASIK ectasia particularly after an abbreviated exposure to ultraviolet light exposure. Materials and methods. Fifty-one eyes of 34 patients were treated with epithelium-off UVA-riboflavin corneal collagen cross-linking for either 20 minutes or 30 minutes as part of a US.FDA clinical study....
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